Female mice genetically predisposed to HER-2/neu-related breast tumors were followed from early life until death.
What the researchers measured
Lifespan, reproductive activity, tumor development, tumor burden, and lung metastases were assessed.
How to read this evidence
Researchers studied cells, isolated tissue, or animals. These experiments can help explain a mechanism, but do not establish benefits or safety in people. Human cells grown in a laboratory also belong in this category.
Results in context
The findings concern a specific cancer-prone mouse strain. They do not establish cancer prevention or lifespan extension in people.
What this does not establish
A tumor-prone transgenic mouse model does not establish human longevity or cancer prevention.
Publication & source
Why this paper is included
The compound is a named subject of the publication title.
Publication indexing
Journal Article · Research Support, Non-U.S. Gov't