Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.
Khavinson VKh, Bondarev IE, Butyugov AA · Bulletin of experimental biology and medicine · PMID 12937682
Study summary
Main finding
The authors reported telomerase-related changes and telomere elongation after exposing cultured fibroblasts to Epithalon, an alternate spelling of Epitalon.
Human fetal fibroblasts that initially lacked detectable telomerase activity were exposed to Epithalon, an alternate spelling of Epitalon, in cell culture.
What the researchers measured
Expression of a telomerase component, telomerase enzyme activity, and telomere length. Telomeres are chromosome-end structures; telomerase can extend them.
How to read this evidence
Researchers studied cells, isolated tissue, or animals. These experiments can help explain a mechanism, but do not establish benefits or safety in people. Human cells grown in a laboratory also belong in this category.
Results in context
The measured outcomes concern chromosome maintenance in cultured cells. A longer telomere in that setting is not a measurement of a person's lifespan, healthspan, or biological age, and cannot establish an anti-aging benefit in people.
What this does not establish
Human cells in a dish are not a human trial. These observations do not establish longer life or reversal of aging in people.
Publication & source
Why this paper is included
The compound is a named subject of the publication title.
Publication indexing
Journal Article
Indexed subjects
Animals · Fibroblasts · Flow Cytometry · HeLa Cells · Humans · In Situ Hybridization, Fluorescence · Oligopeptides · Protein Subunits · Telomerase · Telomere
Source checked
October 4, 2026. Years follow journal issues; online-first dates may differ.