Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA.

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Abstract excerpt

“The site-specific interactions of peptides with DNA can control epigenetically the cell genetic functions, and they seem to play an important role in regulation of…”

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Check the methods for the exact molecule, preparation, and research model. Measurements of a naturally occurring peptide differ from testing its administration. Cell and animal findings need separate evaluation in people.

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Publication & source

Why this paper is included: The study tested HeLa-cell uptake of fluorescently labeled Epithalon and separate in vitro peptide-DNA interactions.
Publication indexing: Journal Article · Research Support, Non-U.S. Gov't
Indexed subjects: Binding Sites · Cell Nucleus · Cytosine · DNA · DNA Methylation · Deoxyribonucleotides · Ethidium · Fluorescein-5-isothiocyanate · Fluorescence · Fluorescent Dyes · HeLa Cells · Humans · Oligopeptides · Transcriptional Activation
Source checked: October 4, 2026. Years follow journal issues; online-first dates may differ.

Open PubMed record PMID 22117547 · Journal and full-text links

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