Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin.
Miller TR, Wagner JD, Baack BR et al. · Archives of facial plastic surgery · PMID 16847171
Study summary
Main finding
Objective evaluations found no significant between-group improvement in redness, wrinkles, or skin quality; patient satisfaction was higher in the GHK-Cu group.
Randomized post-laser skin-care study with 13 completers
How the study was set up
Patients undergoing circumoral CO2 laser resurfacing were randomized to post-procedure skin regimens with or without GHK-Cu; 13 completed the study.
What the researchers measured
Blinded and computer-assisted redness assessments, wrinkle and skin-appearance ratings, and patient questionnaires were assessed through 12 weeks.
How to read this evidence
The paper includes research in people. Its comparison groups, participant selection, follow-up, and measured outcomes determine how far the findings can be applied. The label alone does not establish efficacy or safety.
Results in context
Objective redness, wrinkle, and skin-quality outcomes did not differ significantly between groups. Higher questionnaire satisfaction should be kept separate from those negative objective findings.
What this does not establish
The small study and discrepancy between subjective satisfaction and objective outcomes limit efficacy claims. Results concern the tested topical regimen.
Publication & source
Why this paper is included
The compound is a named subject of the publication title.