The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat.
Rössler AS, Pfaus JG, Kia HK et al. · Pharmacology, biochemistry, and behavior · PMID 17113634
Study summary
Main finding
Sexual solicitation increased with estradiol plus progesterone, but other behavioral measures and estradiol-only conditions did not show the same response.
Ovariectomized female rats under different hormone conditions
How the study was set up
Ovariectomized female rats were given different hormone-priming conditions and tested in repeated paced-mating experiments.
What the researchers measured
Solicitation behaviors, mating pacing, and receptivity were scored.
How to read this evidence
Researchers studied cells, isolated tissue, or animals. These experiments can help explain a mechanism, but do not establish benefits or safety in people. Human cells grown in a laboratory also belong in this category.
Results in context
Some solicitation behaviors increased only with a particular estrogen-plus-progesterone condition; pacing and receptivity did not change. Human sexual desire was not measured.
What this does not establish
Effects depended on the experimental hormonal setting and cannot establish human sexual-function treatment.
Publication & source
Why this paper is included
The compound is a named subject of the publication title.
Publication indexing
Journal Article · Research Support, Non-U.S. Gov't